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Univ.-Prof. Dr. Dr Wolf-Dieter Grimm M.Sc., emeritus
Primary affilation
Dr. Wolf-Dieter Grimm, PhD, MSc, Senior Professor of Periodontology, Periodontology, School of Dental Medicine, Faculty of Health, University of Witten/Herdecke
Secondary affilation
Privat Practice „Praxisteam Haßlinghausen“ specialized on Advanced Periodontology
ORCID: http://orcid.org/0000-0002-0693-0212
Scopus ID: 7102143997
Publons: https://publons.com/uthor/edit/#profile-settingsa
Education and Training
Wolf-Dieter Grimm, clinical periodontist, graduated from dentistry, Pavlov First Saint Petersburg State Medical University in 1968. He worked for Technical University Dresden, for Academy of Postgraduate Programs in Dentistry Schwerin, and University of Witten/Herdecke, Faculty of Health, Germany, 1991 to date. Since 1992, he became the Chairman of Department of Periodontology, Faculty of Dental Medicine, University of Witten/Herdecke and the director of Dental clinics 1993–97. From 1997–2005, he worked in USA as an Adjunct Professor in the Department of Periodontology, University of North Carolina at Chapel Hill. As PI and Professor of Periodontology he has decades of experience with the diagnostic and treatment of periodontal diseases. Prof. Grimm has developed methods for minimal-invasive periodontal surgery including several surgical instruments for micro-surgical treatment of periodontitis. He has developed advanced course for post-graduate training in Periodontal Medicine (Postgraduate Curriculum of Periodontology) provided for dentists specializing in Clinical Periodontics since 2003. Prof. Grimm is Diplomate/Specialist® of Periodontology (German Society of Periodontology/European Federation of Periodontology).
Positions and Employment
During his active research time as visiting research fellow at the Center for Oral and Systemic diseases (Director: Prof. Dr. St. Offenbacher) from 1997 up to 1998 and later on as Adjunct Professor of Periodontology (1998–2005) at the Department of Periodontology (Professor and Chair: Prof Dr. R. Williams) at the University of North Carolina at Chapel Hill, Prof. Grimm has developed rodent (rat and mice) animal models including animal treatment and experimental surgery (titanium chamber model); histological techniques (organ/tissue/cell isolation, fixation, processing for light/scanning electron microscopy, embedding, sectioning, specific/differential staining) and radioactive labeling in vivo/in vitro for the investigation of Periodontal Diseases related to systemic diseases and for periodontal regeneration, now established in cooperation with the Anatomy and the Institute of Immunology, and the Animal facility Campus Witten of the Faculty of Health, Witten/Herdecke University, Germany. In addition to the 2001 Colgate-Research Award, most awards to him were for the basic science in dentistry. Since 2006 he focused on Stem cells in Regenerative Medicine. In standardized animal model, he investigated stem cell-supported periodontal and alveolar bone regeneration in nude rat and in sheep models. In general, my current stem cell research is focused on adult (somatic) stem cells and the regulation of their fundamental biological properties including differentiation, proliferation, and migration. Prof. Grimm is further interested in the impact of pro- and anti-inflammatory signals on mesenchymal stem cells (progenitor of bone, fat and cartilage tissue) and oral-derived neural crest-derived stem cells.
Professional Activities and Memberships
Member of Editorial boards:
Guest Editor:
Deutsche Gesellschaft für Parodontologie:
ad-hoc reviewer for:
Patent: PCT/EP2006/066221 „A post-natal periodontal-derived neural stem cell”